Scientific Publications

ih-gradient-300px

Our science is rooted in evidence-based, peer-reviewed research.

Read from our library. 

Publications

ih-gradient-300px

Tobias
Tobias, J. et al.

Bifidobacterium longum subsp. infantis EVC001 Administration Is Associated With a Significant Reduction In Incidence of Necrotizing Enterocolitis In Very Low Birth Weight Infants

Barrat, M.J. .75 page
Barratt, M. J. et al.

Bifidobacterium infantis treatment promotes weight gain in Bangladeshi infants with severe acute malnutirion

pre-term
Bajorek, S. et al.

B. infantis EVC001 Is Well-Tolerated and Improves Human Milk Oligosaccharide Utilization in Preterm Infants in the Neonatal Intensive Care Unit

Larke, J.A.
Larke, J. A. et al.

Preterm Infant Fecal Microbiota and Metabolite Profiles Are Modulated in a Probiotic Specific Manner

Casaburi Front Pediatr 075
Casaburi, G. et al.

Metabolic model of necrotizing enterocolitis in the premature newborn gut resulting from enteric dysbiosis

Lueschow
Lueschow, S. R. et al.

Bifidobacterium longum subspecies infantis Strain EVC001 Decreases Neonatal Murine Necrotizing Enterocolitis

cell
Henrick, B. M. et al.

Bifidobacteria-mediated immune system imprinting early in life

SCOOP-PDF
Nguyen, M. et al.

Impact of Probiotic B. infantis EVC001 Feeding in Premature Infants on the Gut Microbiome, Nosocomially Acquired Antibiotic Resistance, and Enteric Inflammation

Metagenomic
Casaburi, G. et al.

Metagenomic insights of the infant microbiome community structure and function across multiple sites in the United States

Comparative-Genome-Analysis
Duar, R. et al.

Comparative Genome Analysis of Bifidobacterium longum subsp. infantis Strains Reveals Variation in Human Milk Oligosaccharide Utilization Genes among Commercial Probiotics

Intestinal-Inflammation-in-Infants-_0
Henrick, B. et al.

Colonization by B. infantis EVC001 modulates enteric inflammation in exclusively breastfed infants

Clinical Studies
Frese, S. A. et al.

Persistence of Supplemented Bifidobacterium longum subsp. infantis EVC001 in Breastfed Infants

OBrien
O'Brien, C. E. et al.

Early probiotic supplementation with B. infantis in breastfed infants leads to persistent colonization at 1 year

Symptomatic-relief-from-at-home-use
Dimitratos, S. M. et al.

Symptomatic relief from at-home use of activated Bifidobacterium infants EVC001 probiotic in infants:

Duar FEMS thumbnail
Duar, R. et al.

Reintroducing B. infants to the cesarean-born neonate: an ecologically sound alternative to "vaginal seeding"

Duar HT thumbnail
Duar, R. et al.

Colonization resistance in the infant gut: the role of B. infantis in reducing pH and preventing pathogen growth

Duar Frontiers in Nut thumbnail
Duar, R. et al.

Integrating the ecosystem services framework to define dysbiosis in the breastfed infant gut: The role of B. infantis and human milk oligosaccharides

Smilowitz thumbnail
Smilowitz, J. and Taft, D.

The Infant Gut Microbiome and Probiotics that Work

Early-Life-Gut-Microbiome-Reuced-the-abundance-of-antibiotic-resistant-bacteria
Casaburi, G. et al.

Early-life gut microbiome modulation reduces the abundance of antibiotic-resistant bacteria

Mucin
Karav, S. et al.

Reduced colonic mucin degradation in breastfed infants colonized by Bifidobacterium longum subsp. infantis EVC001

Casaburi Frese Human Micr thumbnail
Casaburi, G. and Frese, S.

Colonization of breastfed infants by Bifidobacterium longum subsp. infantis EVC001 reduces virulence gene abundance

Henrick mSphere thumbnail
Henrick, B. M. et al.

Elevated fecal pH indicates a profound change in the breastfed infant gut microbiome due to a reduction of Bifidobacterium over the past century

Smilowitz BMC thumbnail
Smilowitz, J. et al.

Safety and tolerability of Bifidobacterium longum subspecies infantis EVC001 supplementation in healthy term breastfed infants: a phase I clinical trial

Karav JOFF thumbnail
Karav, S. et al.

N-glycans from human milk glycoproteins are selectively released by and infant gut symbiont in vivo

Disclaimer: INF108 is a drug candidate based on the learnings from EVC001. EVC001 is not approved or intended to prevent, treat, cure, or mitigate any disease. EVC001 is intended for healthy, full-term infants only.

Featured News Coverage

ih-gradient-300px

Our breakthrough findings on B. infantis EVC001 and its impacts on infant health have been addressed in notable publications around the world.